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Integrin beta 2 抗体 (AA 534-546)

This anti-Integrin beta 2 antibody is a 小鼠 单克隆 antibody detecting Integrin beta 2 in FACS, WB, IP 和 IHC. Suitable for 人.
产品编号 ABIN2469881
发货至: 中国

Quick Overview for Integrin beta 2 抗体 (AA 534-546) (ABIN2469881)

抗原

See all Integrin beta 2 (ITGB2) 抗体
Integrin beta 2 (ITGB2)

适用

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宿主

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小鼠

克隆类型

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  • 2
单克隆

标记

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This Integrin beta 2 antibody is un-conjugated

应用范围

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Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC)

克隆位点

MEM-48
  • 抗原表位

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    AA 534-546

    特异性

    Recongizes an epitope involving residues 534-546 in cysteine-rich repeat 3 of the CD18 antigen (integrin beta2 subunit, beta2 integrin).

    纯化方法

    Protein A Column

    免疫原

    Integrin beta 2 monoclonal antibody was raised against Integrin beta 2 (Human).

    亚型

    IgG1
  • 应用备注

    Integrin beta 2 antibody can be used in ELISA starting at 1:100000, Western Blot starting at 1:1000 - 1:10000, and immunohistochemistry starting at 5 μg/mL.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    PBS, 15 mM sodium azide, approx., pH 7.4.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    As with all antibodies avoid freeze/thaw cycles.

    储存条件

    4 °C/-20 °C

    储存方法

    Integrin beta 2 antibody can be stored short term 4 °C. For long term storage aliquot and store at -20 °C.
  • 抗原

    Integrin beta 2 (ITGB2)

    别名

    Integrin beta 2

    背景

    CD18 is a 90-95 kDa type I transmembrane protein expressed on all leukocytes. The ITGB2 protein product is the integrin beta chain beta 2. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, beta 2 combines with the alpha L chain to form the integrin LFA-1, and combines with the alpha M chain to form the integrin Mac-1. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling.

    基因ID

    3689

    UniProt

    P05107

    途径

    NF-kappaB Signaling, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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